Serum CAH/Steroid Panel (LC/MSMS)

Specimen Container

Adult – Gel separator tube
Paediatric – Microtube

Specimen Requirement

Adult – At least 2ml of plain blood
Paediatric – At least 3 microtubes of plain blood

Specimen Storage / Transport

Send specimen directly to the laboratory. Specimen should be separated within 1 hour of sampling. Please send with a separate ice pack.

Method

Orderable as STAT?

No

Turn Around Time

10 working days

Reference Value(s)

Serum Androstenedione		ng/dL
Children		Male	Female
0-1 day		15.0-145.0	15.0-175.0
1-7 days		20.0-110.0	25.0-95.0
7-29 days		25.0-160.0	15.0-90.0
29 days-1 year		15.0-90.0	15.0-145.0
1 year-5 years		15.0-35.0	15.0-45.0
Tanner Stage 1	5 years to 17 years	25.0-190.0 (5.0-9.8 years)	15.0-60.0 (5.0-9.2 years)
Tanner Stage 2		15.0-120.0 (9.8-14.5 years)	30.0-145.0 (9.2-13.7 years)
Tanner Stage 3		18.0-145.0 (10.7-15.4 years)	30.0-200.0 (10.0-14.4 years)
Tanner Stage 4		15.0-220.0 (11.8-16.2 years)	18.0-260.0 (10.7-15.6 years)
Tanner Stage 5		40.0-260.0 (12.8-17.3 years)	18.0-260.0 (11.8-18.6 years)
Adult		Male	Female
≥18 years		15.0-250.0	15.0-250.0

Serum Cortisol	µg/dL
All ages	Male and Female
Time of collection: a.m.	5.0-25.0
Time of collection: p.m.	2.0-14.0

Serum DHEA-S (Dehydroepiandrosterone-sulfate)	µg/dL
Children	Male	Female
0-8 days	85.5-423	68.9-472.0
8-16 days	30.2-176	33.5-350.0
16 days - 4 years	7.4-99.1	7.4-123.0
4-7 years	7.4-228.0	7.4-46.8
7-9 years	7.7-119.0	10.7-78.5
9-11 years	14.7-88.4	12.5-194.0
11-12 years	19.5-191.0	8.5-99.9
12-13 years	11.8-373.0	24.7-226.0
13-14 years	13.6-289.0	21.4-169.0
14-15 years	14.0-300.0	22.1-327.0
15-16 years	52.0-440.0	32.4-351.0
16-17 years	30.2-364.0	56.0-385.0
17-18 years	99.9-344.0	85.5-405.0
Adult	Male	Female
18-31 years	105.0-728.0	83.0-377.0
31-41 years	57.0-522.0	45.0-295.0
41-51 years	34.0-395.0	27.0-240.0
51-61 years	20.0-299.0	16.0-195.0
61-70 years	12.0-227.0	9.7-159.0
≥71 years	6.6-162.0	5.5-124.0

Serum 11-Deoxycortisol	ng/dL
Children	Male and Female
0-29 days	≤344.0
29 days-13years	20.0-250.0
13-17 years	50.0-300.0
Adult	Male and Female
≥18 years	15.0-79.0

Serum 21-Deoxycortisol	ng/dL
All ages	Male and Female
All ages	≤25.0

Serum 17-hydroxyprogesterone	ng/dL
Children	Male and Female
0-29 days	≤630.0
29 days-2 months	≤300.0
2 months-12 months	20.0-200.0
1 year- 11 years	20.0-90.0
11-17 years	20.0-220.0
Adult	Male	Female
≥18 years	≤220.0	Follicular: <80.0
		Luteal: <285.0
		Post-menopausal: <51.0

Serum 21-hydroxyprogesterone (11-Deoxycorticosterone)	ng/dL
Children	Male and Female
0-29 days	≤105.0
29 days -2 years	30.0-49.0
2-11 years	≤34.0
11-17 years	≤30.0
Adult	Male and Female
≥18 years	≤30.0

Serum Testosterone	ng/dL
Children	Male	Female
0-6 months	75.0-400.0	20.0-80.0
6 months-10 years	≤20.0	≤20.0
10-17 years	20.0-950.0	20.0-80.0
Adult	Male	Female
≥18 years	250.0-1000.0	200.0-800.0

Testing Laboratory Location

KKH

Laboratory

NENS Lab

Contact Number

6394 5049

Day and Time Performed

Monday to Friday: 0900 hrs – 1800 hrs

Orderable on CPOE?

Yes

Downtime Form

Biochemical Genetics Lab

Additional Information

Useful For	Detect accumulation of specific steroids as a result of enzyme deficiencies in congenital adrenal hyperplasia (CAH). Monitor patients with CAH.